Search Result

Results for "

Fibroblast growth factor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FGFR (29) IGF-1R (1) PDGFR (1) VEGFR (1) Apoptosis (1) Bacterial (1) c-Met/HGFR (1) Discoidin Domain Receptor (1) Drug Metabolite (1) Endogenous Metabolite (5) ERK (2) Fluorescent Dye (1) Glucocorticoid Receptor (1) HBV (1) Insulin Receptor (1) Isotope-Labeled Compounds (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (23) Cardiovascular Disease (3) Endocrinology (2) Infection (1) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (5)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

135

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: FGFR FAP VEGFR TGF-beta/Smad PDGFR TGF-β Receptor GHSR EGFR IGF-1R Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3601

*Brain Derived Basic Fibroblast* Growth Factor (1-24)** FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

HY-118203

SU4984	FGFR PDGFR Insulin Receptor	Cancer
SU4984 is a protein tyrosine kinase inhibitor, with an IC₅₀ of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits *platelet-derived growth* factor receptor, and insulin receptor**. SU4984 can be used for the research of cancer .

HY-147681

SUN13837	FGFR	Neurological Disease
SUN13837 is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. SUN13837 shows neuroprotective activity. SUN13837 can be used for neurodegenerative diseases research .

HY-147683

FGFR-IN-3	FGFR	Neurological Disease
FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research .

HY-147684

FGFR-IN-7	FGFR	Neurological Disease
FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research .

HY-101493

SUN11602

1 Publications Verification

FGFR Neurological Disease

SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.

SUN11602 1 Publications Verification	FGFR	Neurological Disease
SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.

HY-W001179

2,5-Dihydroxybenzoic acid 1 Publications Verification	Endogenous Metabolite FGFR	Others
2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

HY-P99823

Recifercept TA-46; sFGFR3	FGFR	Others
Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .

HY-17601

Alofanib 3 Publications Verification RPT835	FGFR Apoptosis	Cardiovascular Disease Cancer
Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity .

HY-147619

FGFR-IN-4	FGFR	Cancer
FGFR-IN-4 is a potent inhibitor of FGFR. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase receptor that binds to fibroblast growth factor ligands. FGFR-IN-4 has the potential for the research of cancer diseases (extracted from patent WO2022033532A1, compound 20) . FGFR-IN-4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147620

FGFR-IN-5	FGFR	Cancer
FGFR-IN-5 is a potent inhibitor of FGFR. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase receptor that binds to fibroblast growth factor ligands. FGFR-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2022042612A1, compound 3) . FGFR-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N0060A

Ferulic acid sodium 5 Publications Verification Coniferic acid sodium	FGFR Endogenous Metabolite Reactive Oxygen Species	Cardiovascular Disease Cancer
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N0060

Ferulic acid 5 Publications Verification Coniferic acid	FGFR Endogenous Metabolite	Cancer
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-12823

BLU9931 Maximum Cited Publications 7 Publications Verification	FGFR	Cancer
BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC₅₀ of 3 nM and a K_d of 6 nM. BLU9931 has significant antitumor activity .

HY-D2260

hMSCs-Neu perchlorate	Fluorescent Dye	Neurological Disease
hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .

HY-123453

SM27

NSC 37204
FGFR Cancer

SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation .

SM27 NSC 37204	FGFR	Cancer
SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation .

HY-131908

CPL304110	FGFR	Cancer
CPL304110 is a potent, orally active and selective inhibitor of fibroblast growth factor receptors FGFR (1-3), with IC₅₀ values of 0.75 nM, 0.5 nM, and 3.05 nM for FGFR (1-3), respectively .

HY-W001179R

2,5-Dihydroxybenzoic acid (Standard)	Endogenous Metabolite FGFR	Others
2,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

HY-P99010

Bemarituzumab	FGFR	Cancer
Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research .

HY-N0060S1

Ferulic acid-13C3	Isotope-Labeled Compounds FGFR Endogenous Metabolite	Cancer
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-107194

NSC12	FGFR	Cancer
NSC 12 is an extracellular trap of fibroblast growth factor 2 (FGF2) that binds FGF2 and interferes with its interaction with FGFR1. NSC12 inhibits the proliferation of different FGF-dependent tumour cells both in vitro and in vivo with no systemic toxic effects .

HY-100492

Fisogatinib 1 Publications Verification BLU-554	FGFR	Cancer
Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC₅₀ of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling .

HY-114311

FGFR1/DDR2 inhibitor 1	FGFR Discoidin Domain Receptor	Cancer
FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC₅₀ values of 31.1 nM and 3.2 nM, respectively. Antitumor activity .

HY-N7715

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside	Drug Metabolite	Others
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid (HY-N0060) . Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-147713

FGFR3-IN-1	FGFR	Cancer
FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC₅₀s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer .

HY-P99614

Fazpilodemab BFKB8488A	FGFR	Metabolic Disease
Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD) .

HY-P3503

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (natriuretic peptide receptor type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide can be used in achondroplasia and dwarfism research .

HY-B0636

Triamcinolone acetonide 3 Publications Verification	Glucocorticoid Receptor FGFR	Inflammation/Immunology Endocrinology Cancer
Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis .

HY-100019

Rogaratinib 5 Publications Verification BAY1163877	FGFR	Cancer
Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively .

HY-128341

ERK5-IN-2	ERK	Cardiovascular Disease Cancer
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC₅₀s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis .

HY-132817

Gunagratinib ICP-192	FGFR	Cancer
Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding. Gunagratinib can be used for the research of cancer . Gunagratinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-150687

ZINC12409120	ERK	Metabolic Disease
ZINC12409120 is a high selective ERK inhibitor. ZINC12409120 acts on disrupting FGF23:α-Klotho interaction to inhibit ERK activity with an IC₅₀ of 5.0 μM .

HY-156618

Irpagratinib ABSK011	FGFR	Cancer
Irpagratinib (ABSK011) is an orally active inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase, targeting to FGFR4 (IC50<10 nM). Irpagratinib inhibits the auto-phosphorylation of FGFR4 and blocks signal transduction from FGFR4 to downstream pathway activation. Irpagratinib exhibits high exposure in PK study in mouse, rat and dog, and also shows antineoplastic/anti-tumor activity in subcutaneous xenograft tumor models .

HY-125102

AZ12253801	IGF-1R	Cancer
AZ12253801 is an ATP-competitive IGF-1R tyrosine kinase inhibitor that shows ∼10-fold selectivity over the insulin receptor. AZ12253801 inhibits IGF-1R–driven proliferation in 3T3 mouse fibroblasts (transfected with human IGF-1R) with an IC₅₀ of 17 nmol/L. The IC₅₀ for epidermal growth factor receptor (EGFR)–driven proliferation is 440 nmol/L. Anti-tumor activity.

HY-108933

JK-P3	VEGFR FGFR	Cancer
JK-P3 is a potent and pan VEGFR2 inhibitor, with IC₅₀s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor kinase activity in vitro. JK-P3 has anti-angiogenic activity .

HY-P99196

Ficlatuzumab	c-Met/HGFR	Cancer
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion .

Cat. No.	Product Name

HY-L088

Angiogenesis-Related Compound Library	2,003 compounds
Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer). MCE offers a unique collection of 2,003 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis-related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

2,003 compounds

Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer).

MCE offers a unique collection of 2,003 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis-related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

HY-L038

Differentiation Inducing Compound Library	1,447 compounds
Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method. MCE Differentiation Inducing Compound Library contains a unique collection of 1,447 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Differentiation Inducing Compound Library

1,447 compounds

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 1,447 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

hMSCs-Neu perchlorate	Fluorescent Dyes/Probes
hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .

N-Deacetylase/N-Sulfotransferase 1 EC:2.8.2.8; NDST1	Enzyme Substrates
N-Deacetylase/N-Sulfotransferase 1 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 1 modifies heparan sulfate-dependent growth factor and morphogen signalling .

*Brain Derived Basic Fibroblast* Growth Factor (1-24)** FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

FNLPLGNYKKP	Peptides	Inflammation/Immunology
FNLPLGNYKKP is a peptide fragment of brain-derived acidic fibroblast growth factor.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W001179

2,5-Dihydroxybenzoic acid 1 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite FGFR
2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

HY-N0060A

Ferulic acid sodium 5 Publications Verification Coniferic acid sodium	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Endogenous metabolite Disease Research Fields Cancer	FGFR Endogenous Metabolite Reactive Oxygen Species
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N0060

Ferulic acid 5 Publications Verification Coniferic acid	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols other families Simple Phenylpropanols Sunscreen Phenols Phenylpropanoids Cosmetic Research Disease Research Fields Cancer	FGFR Endogenous Metabolite
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N7715

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside	Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Rosaceae Phenols Phenylpropanoids Plants Aruncus sylvester Kostel. Disease Research Fields	Drug Metabolite
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid (HY-N0060) . Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-W001179R

2,5-Dihydroxybenzoic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite FGFR
2,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

Recombinant Proteins Recommended:

Fibroblast Growth Factor

Species:	Human (91) Rhesus Macaque (5) Bovine (2) Rat (6) Mouse (23) Cynomolgus (3) Pig (1) Canine (2)
Tag:	His (76) SUMO (3) Tag Free (36) Avi (6) Myc (1) GST (2) Fc (24) Flag (1) B2M (1)
Source:	HEK293 (57) CHO (2) P. pastoris (3) Sf9 insect cells (6) E. coli (67)

Cat. No.	Compare	Product Name	Species	Source

HY-P701238

FGF-basic Protein, Salmon

Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB
Others E. coli

HY-P71959A

	FGF-12 Protein, Human (181a.a, His) EIEE47; FGF-12; Fgf12; FGF12_HUMAN; FGF12B; FHF-1; FHF1; Fibroblast growth factor 12; Fibroblast growth factor 12B; Fibroblast growth factor FGF 12b; Fibroblast growth factor homologous factor 1; Myocyte activating factor; Myocyte-activating factor	Human	E. coli
	FGF-12, vital for nervous system development, positively regulates voltage-gated sodium channels, particularly SCN8A, enhancing neuronal excitability. It achieves this by elevating the voltage dependence of SCN8A fast inactivation. FGF-12 interacts specifically with the C-terminal region of SCN9A. FGF-12 Protein, Human (181a.a, His) is the recombinant human-derived FGF-12 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGF-12 Protein, Human (181a.a, His) is 181 a.a., with molecular weight of ~23 kDa.

HY-P700476

	FGF2 Protein, Bovine (His) 1 Publications Verification Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Bovine	E. coli
	FGF2 protein is a multifunctional ligand that can bind to FGFR1, FGFR2, FGFR3 and FGFR4. It is also a key integrin ligand for FGF2 signal transduction and has an important interaction with the integrin ITGAV:ITGB3. FGF2 plays a critical role in cell survival, division, differentiation, and migration, serves as a potent mitogen, and induces angiogenesis. FGF2 Protein, Bovine (His) is the recombinant bovine-derived FGF2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGF2 Protein, Bovine (His) is 146 a.a., with molecular weight of 20.5 kDa.

HY-P700630

	FGF2 Protein, Chicken (His) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Others	E. coli
	FGF2 Protein acts as a ligand for FGFR1-4 and an integrin ligand for FGF2 signaling. It regulates cell survival, division, differentiation, and migration. FGF2 Protein is a strong mitogen and can induce angiogenesis. FGF2 Protein, Chicken (His) is the recombinant FGF2 protein, expressed by E. coli, with C-6*His labeled tag. The total length of FGF2 Protein, Chicken (His) is 146 a.a., with molecular weight of 23.2 kDa.

HY-P701242

	Heat Stable FGF-basic Protein, Human 4 Publications Verification Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF basic, or bFGF (fibroblast growth factor basic), initiates at an alternative CUG codon, marking a distinctive feature in translational initiation. This alternative start codon plays a pivotal role in regulating the expression and functional properties of FGF basic. Heat Stable FGF-basic Protein, Human is the recombinant human-derived Heat Stable FGF-basic protein, expressed by E. coli , with tag free. The total length of Heat Stable FGF-basic Protein, Human is 154 a.a., with molecular weight of ~17.1 kDa.

HY-P700289

	FGF-1 Protein, Human (154a.a) 1 Publications Verification Fibroblast growth factor 1; FGF-1; Acidic Fibroblast growth factor; aFGF; Endothelial Cell growth factor; ECGF; Heparin-Binding growth factor 1; HBGF-1; FGF1; FGFA	Human	E. coli
	FGF-1 Protein intricately regulates cell survival, division, angiogenesis, differentiation, and migration. Acting as a potent mitogen, it serves as a ligand for FGFR1 and integrins. Binding to FGFR1, especially with heparin, leads to dimerization and activation, initiating signaling cascades. Additionally, FGF-1 Protein binds to integrin ITGAV:ITGB3, forming a ternary complex crucial for FGF1 signaling. Inducing phosphorylation of key proteins, it plays a multifaceted role in diverse cellular processes, emphasizing its significance in cell physiology. FGF-1 Protein, Human (154a.a) is the recombinant human-derived FGF-1 protein, expressed by E. coli, with His, tag free. The total length of FGF-1 Protein, Human (154a.a) is 154 a.a., with molecular weight of 18.54 kDa.

HY-P70438

	FGF-1 Protein, Mouse/Rat Fibroblast growth factor 1; FGF-1; Acidic Fibroblast growth factor; aFGF; Heparin-Binding growth factor 1; HBGF-1; Fgf1; Fgf-1; Fgfa	Rat;Mouse	E. coli
	The FGF-1 protein plays a key role in regulating a variety of cellular processes, serving as a potent mitogen and ligand for FGFR1 and integrins. In the presence of heparin, FGF-1 binds to FGFR1, initiating dimerization and autophosphorylation, resulting in multiple signaling cascades. FGF-1 Protein, Mouse/Rat is the recombinant rat, mouse-derived FGF-1 protein, expressed by E. coli , with tag free. The total length of FGF-1 Protein, Mouse/Rat is 140 a.a., with molecular weight of ~16.0 kDa.

HY-P700237AF

	Animal-Free FGF-2 Protein, Pig (His) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Pig	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.Animal-Free FGF-2 Protein, Pig (His), consists of 1 amino acids, produced by E.coli with tag free.

HY-P70439

	FGF-2 Protein, Mouse (154a.a) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Mouse	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.FGF-2 Protein, Mouse (154a.a), consists of 154 amino acids, produced by E.coli with tag free.

HY-P70440

	FGF basic/bFGF Protein, Human (157a.a) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.FGF basic/bFGF Protein, Human (157a.a), consists of 157 amino acids, produced by E.coli with tag free.

HY-P70600

	FGF basic/bFGF Protein, Human (K128N) 1 Publications Verification Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.FGF basic/bFGF Protein, Human (K128N), consists of 155 amino acids, produced by E.coli with tag free.

HY-P700287

	FGF-17 Protein, Human (194a.a) Fibroblast growth factor 17; FGF-17; FGF17; HH20 Protein, Human; Fibroblast growth factor 17	Human	E. coli
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. FGF-17 Protein, Human (194a.a) is the recombinant human-derived FGF-17 protein, expressed by E. coli, with tag free. The total length of FGF-17 Protein, Human (194a.a) is 194 a.a., with molecular weight of 23 kDa.

HY-P700054AF

	Animal-Free FGF-11 isoform 1 Protein, Human (His) Fibroblast growth factor 11; FHF-3; FHF3; Fibroblast growth factor homologous factor 3	Human	E. coli
	FGF-11 isoform 1 Protein likely participates in the development and functioning of the nervous system, suggesting its role in orchestrating intricate processes that contribute to the establishment and maintenance of neural structures and activities. Animal-Free FGF-11 isoform 1 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-11 isoform 1 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free FGF-11 isoform 1 Protein, Human (His) is 225 a.a., with molecular weight of ~25.81 kDa.

HY-P700055AF

	Animal-Free FGF-11 isoform 2 Protein, Human (His) Fibroblast growth factor 11; FHF-3; FHF3; Fibroblast growth factor homologous factor 3	Human	E. coli
	FGF-11 isoform 2 protein is a member of the fibroblast growth factor family, characterized by broad mitotic and cell survival activities, affecting embryonic development, cell growth, morphogenesis, tissue repair, and tumor growth. Its specific function has not yet been determined, but the expression pattern of its mouse homolog suggests a role in nervous system development. Animal-Free FGF-11 isoform 2 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-11 isoform 2 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free FGF-11 isoform 2 Protein, Human (His) is 166 a.a., with molecular weight of ~19.34 kDa.

HY-P700477

	FGF2 Protein, Bovine (P. pastoris, N-His) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Bovine	P. pastoris
	FGF2 Protein, a versatile ligand, binds to FGFR1, FGFR2, FGFR3, and FGFR4, also functioning as a crucial integrin ligand for FGF2 signaling, with essential interaction involving integrin ITGAV:ITGB3. Playing a pivotal role in cell survival, division, differentiation, and migration, FGF2 acts as a potent mitogen and induces angiogenesis. It promotes retinal lens fiber differentiation through ERK1/2 phosphorylation. Existing as a monomer or homodimer, FGF2 interacts with receptors and forms complexes with proteins like CSPG4, FGFBP1, TEC, and FGFBP3, emphasizing its diverse cellular functions. The interaction with integrin ITGAV:ITGB3 is indispensable for FGF2 signaling, and additional interactions with SNORC and glypican GPC3 illustrate the intricate network of FGF2-associated proteins. FGF2 Protein, Bovine (P. pastoris, N-His) is the recombinant bovine-derived FGF2 protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of FGF2 Protein, Bovine (P. pastoris, N-His) is 146 a.a., with molecular weight of 18.4 kDa.

HY-P700487

	FGF2 Protein, Chicken (N-His, C-Myc) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Others	E. coli
	FGF2 Protein acts as a ligand for FGFR1-4 and an integrin ligand for FGF2 signaling. It regulates cell survival, division, differentiation, and migration. FGF2 Protein is a strong mitogen and can induce angiogenesis. FGF2 Protein, Chicken (N-His, C-Myc) is the recombinant FGF2 protein, expressed by E. coli, with C-Myc, N-10*His labeled tag. The total length of FGF2 Protein, Chicken (N-His, C-Myc) is 146 a.a., with molecular weight of 23.8 kDa.

HY-P700479

	FGF basic/bFGF Protein, Human (P. pastoris, N-His) Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Human	P. pastoris
	FGF basic, or bFGF (fibroblast growth factor basic), initiates at an alternative CUG codon, marking a distinctive feature in translational initiation. This alternative start codon plays a pivotal role in regulating the expression and functional properties of FGF basic. FGF basic/bFGF Protein, Human (P. pastoris, N-His) is the recombinant human-derived FGF basic/bFGF protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of FGF basic/bFGF Protein, Human (P. pastoris, N-His) is 146 a.a., with molecular weight of 17.9 kDa.

HY-P70533

FGF-8b Protein, Human/Mouse

Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B
Mouse;Human E. coli

HY-P72803

	FGF-13 Protein, Human Fibroblast growth factor 13; FGF-13; FHF-2	Human	E. coli
	FGF-13 Protein, a microtubule-binding protein, directly binds and stabilizes tubulin, influencing microtubule polymerization. It negatively regulates axonal and leading process branching, crucial for neuron polarization and migration in the cerebral cortex and hippocampus. Additionally, FGF-13 regulates voltage-gated sodium channel transport and function, potentially impacting MAPK signaling. Interactions with SCN8A, SCN1A, SCN5A, SCN2A, and SCN11A suggest a role in modulating sodium channel activity and MAPK8IP2 scaffolding. FGF-13 Protein, Human is the recombinant human-derived FGF-13 protein, expressed by E. coli , with tag free. The total length of FGF-13 Protein, Human is 245 a.a., with molecular weight of ~27.6 kDa.

HY-P77365

	FGF14 Protein, Canine Fibroblast growth factor 14; FHF-4; FGF14	Canine	E. coli
	Fibroblast growth factor 14 is a bioactive protein found in the brain and pituitary gland that promotes fibroblast growth and is involved in embryonic development, angiogenesis, tissue repair and other processes. FGF14 plays a neuroprotective role in in vitro Alzheimer's disease (AD) models by inhibiting MAPK signaling. FGF14 Protein, Canine is the recombinant canine-derived FGF14 protein, expressed by E. coli , with tag free. The total length of FGF14 Protein, Canine is 189 a.a., with molecular weight of ~21 kDa.

HY-P7047A

	KGF/FGF-7 Protein, Human (CHO) rHuKGF-1/FGF-7; Keratinocyte growth factor; Fibroblast growth factor-7; HBGF-7	Human	CHO
	KGF/FGF-7 Protein, Human (CHO) is a polypeptide mitogen that belongs to the family of fibroblast growth factors, binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells. KGF/FGF-7 Protein and its receptor are important for normal wound healing.

HY-P7342AF

	Animal-Free KGF-2/FGF-10 Protein, Human (His) FGF-10; Fibroblast growth factor-10; Keratinocyte growth factor-2	Human	E. coli
	KGF-2/FGF-10 Protein orchestrates embryonic development, regulating cell proliferation and differentiation, with indispensable significance in branching morphogenesis. This versatile protein potentially contributes to wound healing. Engaging with FGFR1 and FGFR2, it forms molecular complexes, highlighting its multifaceted functions. Interactions with FGFBP1 emphasize its intricate network in orchestrating cellular responses and developmental events during embryogenesis. Animal-Free KGF-2/FGF-10 Protein, Human (His) is the recombinant human-derived animal-FreeKGF-2/FGF-10 protein, expressed by E. coli, with C-His, C-His labeled tag. The total length of Animal-Free KGF-2/FGF-10 Protein, Human (His) is 169 a.a., with molecular weight of ~20.06 kDa.

HY-P700279

	KGF-2/FGF-10 Protein, Human (N-His) rHuFGF-10, His; Fibroblast growth factor-10; Keratinocyte growth factor-2	Human	E. coli
	KGF-2/FGF-10 Protein orchestrates embryonic development, regulating cell proliferation and differentiation, with indispensable significance in branching morphogenesis. This versatile protein potentially contributes to wound healing. Engaging with FGFR1 and FGFR2, it forms molecular complexes, highlighting its multifaceted functions. Interactions with FGFBP1 emphasize its intricate network in orchestrating cellular responses and developmental events during embryogenesis. KGF-2/FGF-10 Protein, Human (N-His) is the recombinant human-derived KGF-2/FGF-10 protein, expressed by E. coli, with N-His labeled tag. The total length of KGF-2/FGF-10 Protein, Human (N-His) is 169 a.a., with molecular weight of 21-23 kDa.

HY-P70673

	KGF/FGF-7 Protein, Human (HEK293, His) Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7	Human	HEK293
	KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation. Its critical role extends to normal branching morphogenesis. KGF/FGF-7 Protein, Human (HEK293, His) is the recombinant human-derived KGF/FGF-7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of KGF/FGF-7 Protein, Human (HEK293, His) is 163 a.a., with molecular weight of 20-28 kDa.

HY-P7349A

	FGF-8e Protein, Human (N-His) Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B	Human	E. coli
	FGF-8e Protein, Human is an isoform of FGF-8, an essential factor during embryonic development, involved in the progression of prostate cancer.

HY-P700480

	FGF-5 Protein, Human (GST) Fibroblast growth factor 5; Heparin-binding growth factor 5; HBGF-5; Smag-82; FGF5	Human	E. coli
	FGF-5 Protein critically regulates cell proliferation and differentiation, specifically in the hair growth cycle. It plays a key role in normal hair follicle progression, inhibiting hair elongation by promoting the transition from anagen to catagen phases. Interacting with FGFR1 and FGFR2, FGF-5's multifaceted actions underscore its pivotal role in coordinating critical cellular processes for hair growth and maintenance. The presence of heparan sulfate glycosaminoglycans enhances FGF-5's affinity with fibroblast growth factors and receptors, emphasizing its significance in dynamic tissue development regulation. FGF-5 Protein, Human (GST) is the recombinant human-derived FGF-5 protein, expressed by E. coli, with N-GST labeled tag. The total length of FGF-5 Protein, Human (GST) is 251 a.a., with molecular weight of 54.6 kDa.

HY-P70597

	KGF/FGF-7 Protein, Human (163a.a) Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF	Human	E. coli
	KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation. Its critical role extends to normal branching morphogenesis. KGF/FGF-7 Protein, Human (163a.a) is the recombinant human-derived KGF/FGF-7 protein, expressed by E. coli , with tag free. The total length of KGF/FGF-7 Protein, Human (163a.a) is 163 a.a., with molecular weight of 15-20 kDa.

HY-P700070AF

Animal-Free FGF-8b Protein, Human (His)

Fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B
Human E. coli

HY-P70473

	FGF-21 Protein, Human (His) Fibroblast growth factor 21; FGF-21; FGF21	Human	E. coli
	FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Human (His) is the recombinant human-derived FGF-21 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGF-21 Protein, Human (His) is 181 a.a., with molecular weight of ~23.0 kDa.

HY-P70583

	FGF-19 Protein, Human (His) Fibroblast growth factor 19; FGF-19; FGF19	Human	E. coli
	FGF-19 protein plays a crucial role in regulating bile acid biosynthesis by inhibiting CYP7A1 expression through positive regulation of JNK and ERK1/2 cascades. It stimulates glucose uptake in adipocytes, dependent on KLB and FGFR4. FGF-19 Protein, Human (His) is the recombinant human-derived FGF-19 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGF-19 Protein, Human (His) is 190 a.a., with molecular weight of ~26.0 kDa.

HY-P72649

	FGF-4 Protein, Mouse Fibroblast growth factor 4; FGF-4; HBGF-4; HST	Mouse	E. coli
	The FGF-4 protein plays a key role in embryonic development and is central to cell proliferation and differentiation. It is essential for the survival of mouse embryos after implantation and is key to normal limb and heart valve development. FGF-4 Protein, Mouse is the recombinant mouse-derived FGF-4 protein, expressed by E. coli , with tag free. The total length of FGF-4 Protein, Mouse is 136 a.a., with molecular weight of ~15 kDa.

HY-P700062AF

	Animal-Free FGF-20 Protein, Human (His) Fibroblast growth factor 20; FGF20	Human	E. coli
	FGF-20 protein, a homodimer, functions as a neurotrophic factor essential for regulating central nervous system development and function. It interacts with specific receptors, FGFR2 and FGFR4, with heparan sulfate glycosaminoglycans enhancing the binding affinity between fibroblast growth factors (FGFs) and their receptors, serving as coreceptors in this intricate signaling process. Animal-Free FGF-20 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-20 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free FGF-20 Protein, Human (His) is 209 a.a., with molecular weight of ~24.24 kDa.

HY-P7012

	FGF-21 Protein, Human rHuFGF-21; Fibroblast growth factor-21(FGF-21)	Human	E. coli
	FGF-21 Protein, Human is an atypical member of the ﬁbroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.

HY-P70597G

	GMP KGF/FGF-7 Protein, Human (163a.a) Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF	Human	E. coli
	KGF/FGF-7 Protein orchestrates embryonic development, regulating fundamental processes like cell proliferation and differentiation. Its pivotal role extends to normal branching morphogenesis. As a growth factor for keratinocytes, KGF/FGF-7 governs epithelial cell proliferation. Key interactions with FGFBP1 and FGFR2, along with heightened binding affinity through heparan sulfate glycosaminoglycans, underscore KGF/FGF-7's crucial role as a paracrine effector in molecular interactions during embryonic development. GMP KGF/FGF-7 Protein, Human (163a.a) is the recombinant human-derived KGF/FGF-7 protein, expressed by E. coli, with tag free. The total length of GMP KGF/FGF-7 Protein, Human (163a.a) is 163 a.a., with molecular weight of 15-18 kDa.

HY-P700067AF

Animal-Free FGF-5 Protein, Human (His)

Fibroblast growth factor 5; Heparin-binding growth factor 5; HBGF-5; Smag-82; FGF5
Human E. coli

HY-P700494

	FGF-22 Protein, Human (His-SUMO) Fibroblast growth factor 22; FGF22; FGF-22	Human	E. coli
	FGF-22 Protein, multifaceted in physiological processes, influences fasting response, glucose homeostasis, lipolysis, and lipogenesis. It stimulates in vitro cell proliferation and may contribute to hair development. Functionally, FGF-22 forms complexes with FGFR1 and FGFR2, integral to FGF signaling pathways. Interactions with FGFBP1 highlight its role in finely tuned regulatory networks governing cellular and metabolic activities. FGF-22 Protein, Human (His-SUMO) is the recombinant human-derived FGF-22 protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of FGF-22 Protein, Human (His-SUMO) is 148 a.a., with molecular weight of 30.1 kDa.

HY-P7344

	FGF-16 Protein, Human (CHO) rHuFGF-16; FGF-16; Fibroblast growth factor-16	Human	CHO
	FGF-16 Protein, Human (CHO) is a polypeptide chain containing 206 amino acids produced in CHO cells. FGF-16 is a heparin binding growth factor, a member of the FGF family.

HY-P72650

	FGF-21 Protein, Cynomolgus (HEK293, His) FGF21; Fibroblast growth factor 21; FGF-21	Cynomolgus	HEK293
	FGF-21 is a metabolic regulator and a potential anti-diabetic agent. FGF-21 regulates energy balance and glucose and lipid homeostasis through a heterodimeric receptor complex comprising FGFR1 and 尾-klotho. FGF-21 can also signal through FGFR2 and FGFR3. FGF-21 can be used for research of obesity, NASH, NAFLD, and type 2 diabetes mellitus. FGF-21 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGF-21 Protein, Cynomolgus (HEK293, His) is 181 a.a., with molecular weight of 19-24 kDa.

HY-P72651

	FGF-21 Protein, Mouse (HEK293, His) FGF21; Fibroblast growth factor 21; FGF-21	Mouse	HEK293
	FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGF-21 Protein, Mouse (HEK293, His) is 182 a.a., with molecular weight of 20-29 kDa.

HY-P72654

	FGF-12 Protein, Human Fibroblast growth factor 12; FGF-12; FHF-1; FGF12B	Human	E. coli
	FGF-12, vital for nervous system development, positively regulates voltage-gated sodium channels, particularly SCN8A, enhancing neuronal excitability. It achieves this by elevating the voltage dependence of SCN8A fast inactivation. FGF-12 interacts specifically with the C-terminal region of SCN9A. FGF-12 Protein, Human is the recombinant human-derived FGF-12 protein, expressed by E. coli , with tag free. The total length of FGF-12 Protein, Human is 181 a.a., with molecular weight of 18-20 kDa.

HY-P70440G

	GMP FGF basic/bFGF Protein, Human Fibroblast growth factor 2; FGF-2; bFGF; HBGF-2	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.GMP FGF basic/bFGF Protein, Human, consists of 157 amino acids, produced by E.coli with tag free.

HY-P75193

	FGF-14 Protein, Human (isoform 1B) Fibroblast growth factor 14; FHF-4; FGF14	Human	E. coli
	FGF-14 Protein likely plays a crucial role in the development and functioning of the nervous system, contributing to intricate processes underlying neural structure and activity. Its interaction with SCN8A suggests potential involvement in modulating this sodium channel's activity, emphasizing its intricate role in neurophysiology. FGF-14 Protein, Human (isoform 1B) is the recombinant human-derived FGF-14 protein, expressed by E. coli , with tag free. The total length of FGF-14 Protein, Human (isoform 1B) is 189 a.a., with molecular weight of ~18 kDa.

HY-P75762

	FGF-21 Protein, Hamster (HEK293, His) FGF21; Fibroblast growth factor 21; FGF-21	Others	HEK293
	FGF21 is a liver factor that signals through the FGF21 receptor in the paraventricular nucleus of the hypothalamus to regulate monosaccharide intake and preference for sweets. FGF21 promotes the progression of non-small cell lung cancer by activating the SIRT1/PI3K/AKT signaling pathway. FGF21 plays an important role in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 Protein, Hamster (HEK293, His) is the recombinant FGF-21 protein, expressed by HEK293 , with C-His labeled tag. The total length of FGF-21 Protein, Hamster (HEK293, His) is 209 a.a., with molecular weight of ~21.16 kDa.

HY-P76925

	FGF12 Protein, Canine Fibroblast growth factor 12; FGF-12; FHF-1; FGF12B	Canine	E. coli
	FGF12 forms complexes with signaling proteins regulates the cytoskeletal system, binds to FGF receptors, activates signaling cascades to prevent apoptosis and interacts with ribosome biogenetic complexes. FGF12 has been linked to neurological diseases, cancer and heart disease, making it a potential target and therapeutic agent for gene therapy. FGF12 Protein, Canine is the recombinant canine-derived FGF12 protein, expressed by E. coli , with tag free. The total length of FGF12 Protein, Canine is 181 a.a., with molecular weight of ~20 kDa.

HY-P72652

	FGF-17 Protein, Human (HEK293, His) Fibroblast growth factor 17; FGF-17; FGF17	Human	HEK293
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. FGF-17 Protein, Human (HEK293, His) is the recombinant human-derived FGF-17 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGF-17 Protein, Human (HEK293, His) is 194 a.a., with molecular weight of ~31 kDa.

HY-P70583AF

	Animal-Free FGF-19 Protein, Human (His) Fibroblast growth factor 19; FGF-19; FGF19	Human	E. coli
	FGF-19 protein plays a crucial role in regulating bile acid biosynthesis by inhibiting CYP7A1 expression through positive regulation of JNK and ERK1/2 cascades. It stimulates glucose uptake in adipocytes, dependent on KLB and FGFR4. Animal-Free FGF-19 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-19 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free FGF-19 Protein, Human (His) is 194 a.a., with molecular weight of ~22.62 kDa.

HY-P700057AF

	Animal-Free FGF-13 Protein, Human (His) Fibroblast growth factor 13; FGF-13; FHF-2	Human	E. coli
	FGF-13 Protein, a microtubule-binding protein, directly binds and stabilizes tubulin, influencing microtubule polymerization. It negatively regulates axonal and leading process branching, crucial for neuron polarization and migration in the cerebral cortex and hippocampus. Additionally, FGF-13 regulates voltage-gated sodium channel transport and function, potentially impacting MAPK signaling. Interactions with SCN8A, SCN1A, SCN5A, SCN2A, and SCN11A suggest a role in modulating sodium channel activity and MAPK8IP2 scaffolding. Animal-Free FGF-13 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-13 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free FGF-13 Protein, Human (His) is 245 a.a., with molecular weight of ~21.23 kDa.

HY-P700058AF

	Animal-Free FGF-14 Protein, Human (His) Fibroblast growth factor 14; FHF-4; FGF14	Human	E. coli
	FGF-14 Protein likely plays a crucial role in the development and functioning of the nervous system, contributing to intricate processes underlying neural structure and activity. Its interaction with SCN8A suggests potential involvement in modulating this sodium channel's activity, emphasizing its intricate role in neurophysiology. Animal-Free FGF-14 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-14 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free FGF-14 Protein, Human (His) is 245 a.a., with molecular weight of ~28.28 kDa.

HY-P700060AF

	Animal-Free FGF-17 Protein, Human (His) Fibroblast growth factor 17; FGF-17; FGF17	Human	E. coli
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. Animal-Free FGF-17 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-17 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free FGF-17 Protein, Human (His) is 194 a.a., with molecular weight of ~23.32 kDa.

HY-P700063AF

	Animal-Free FGF-22 Protein, Human (His) Fibroblast growth factor 22; FGF22; FGF-22	Human	E. coli
	FGF-22 Protein, multifaceted in physiological processes, influences fasting response, glucose homeostasis, lipolysis, and lipogenesis. It stimulates in vitro cell proliferation and may contribute to hair development. Functionally, FGF-22 forms complexes with FGFR1 and FGFR2, integral to FGF signaling pathways. Interactions with FGFBP1 highlight its role in finely tuned regulatory networks governing cellular and metabolic activities. Animal-Free FGF-22 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-22 protein, expressed by E. coli, with N-SUMO, N-His labeled tag. The total length of Animal-Free FGF-22 Protein, Human (His) is 148 a.a., with molecular weight of ~29.35 kDa.

Cat. No.	Product Name	Chemical Structure

HY-N0060S1

Ferulic acid-13C3
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

Cat. No.	Product Name	Application	Reactivity

HY-P80671

FGF2 Antibody FGF2; FGFB; Fibroblast growth factor 2; FGF-2; Basic Fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2	WB, IP, FC, IHC-P	Human, Mouse
FGF2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 31 kDa, targeting to FGF2. It can be used for WB assays with tag free, in the background of Human.

HY-P81685

FGF1 Antibody (YA1430) FGF1; FGFA; Fibroblast growth factor 1; FGF-1; Acidic Fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1	WB, IHC-P	Human, Mouse, Rat

HY-P82927

FGF19 Antibody (YA2672)

FGF15; FGF19; Fibroblast growth factor 15; Fibroblast growth factor 19
WB Human

HY-P80733

KGF Antibody Fgf7; Fibroblast growth factor 7; HBGF7; Heparin binding growth factor 7; Keratinocyte growth factor	WB	Human, Mouse, Rat
KGF Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to KGF. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P83531

FGF21 Antibody (YA3276)

Fgf21; FGFL; Fibroblast growth factor 21; PRO10196; UNQ3115
WB, IHC-P Human, Mouse, Rat
HY-P81843

FGFR4 Antibody (YA1588)

FGFR4; JTK2; TKF; Fibroblast growth factor receptor 4; FGFR-4; CD334
WB Human, Mouse, Rat
HY-P81655

FRS2 Antibody (YA1400)

Fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1
WB, IP Human

HY-P82931

CD266 Antibody (YA2676) CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat

HY-P81108

HGF Antibody HGF alpha; HGFA; F TCF; Hepatocyte growth factor; Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor precursor; Hepatopoietin A; HPTA; Lung Fibroblast derived mitogen; Scatter factor; SF; hepatocyte growth factor alpha-chain; Hepatocyte growth factor alpha chain; HGF_HUMAN.	ELISA; IHC-P; IHC-F; IF	Human, Mouse(predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig)
HGF Antibody is an unconjugated, approximately 54/80 kDa, rabbit-derived, anti-HGF polyclonal antibody. HGF Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat, dog, pig, cow, horse, rabbit, sheep, guinea pig background without labeling.

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